Protein Information

Cytoscape View


UniProt AC / UniProt ID O14862 / AIM2_HUMAN
Protein Name Interferon-inducible protein AIM2
Gene Name Name: AIM2
Organism Homo sapiens (Human)

PRO ID PR:O14862
DAG View
PRO Name interferon-inducible protein AIM2 (human)
Definition An interferon-inducible protein AIM2 that is encoded in the genome of human.
Short Label hAIM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14862 (AIM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K39 Ubiquitination PhosphoSitePlus
K64 Methylation PhosphoSitePlus
T65 Phosphorylation IEDB 35494241
K71 Acetylation PhosphoSitePlus
K79 Acetylation PhosphoSitePlus
K85 Acetylation PhosphoSitePlus
K160 Acetylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T65 I65 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
K235 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T254 R254 Biomuta DOID:1324 / lung cancer [ cosmic ]
T254 M254 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]