iPTMnet Report for O14830 (PPEF2)
Protein Information
| UniProt AC / UniProt ID | O14830 / PPE2_HUMAN |
| Protein Name | Serine/threonine-protein phosphatase with EF-hands 2 |
| Gene Name | Name: PPEF2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O14830 |
| PRO Name | serine/threonine-protein phosphatase with EF-hands 2 (human) |
| Definition | A serine/threonine-protein phosphatase with EF-hands 2 that is encoded in the genome of human. |
| Short Label | hPPEF2 |
| Category | organism-gene |
DAG ViewO14830 (PPEF2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y33 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y145 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y151 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S353 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S356 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S357 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T410 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y466 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S487 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T530 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K634 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y33 | D33 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| Y33 | C33 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y151 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S357 | L357 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic, icgc ] | |
| K634 | N634 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] |
