iPTMnet Report for O14795 (UNC13B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14795 / UN13B_HUMAN
Protein Name Protein unc-13 homolog B
Gene Name Name: UNC13B
Synonyms:UNC13;
Organism Homo sapiens (Human)

PRO ID PR:O14795
DAG View
PRO Name protein unc-13 homolog B (human)
Definition A protein unc-13 homolog B that is encoded in the genome of human.
Short Label hUNC13B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14795 (UNC13B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation PhosphoSitePlus   UniProt 23186163
K19 Ubiquitination PhosphoSitePlus
T84 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
Y157 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus   UniProt 24275569
S222 Phosphorylation PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
Y243 Phosphorylation PhosphoSitePlus
Y247 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus   UniProt 24275569
S301 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S367 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K438 Ubiquitination PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
S509 O-Glycosylation GlyGen 30379171
K577 Methylation PhosphoSitePlus
K585 Ubiquitination PhosphoSitePlus
T586 Phosphorylation PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
T605 Phosphorylation PhosphoSitePlus
K637 Ubiquitination PhosphoSitePlus
K674 Ubiquitination PhosphoSitePlus
Y812 Phosphorylation PhosphoSitePlus
S912 Phosphorylation PhosphoSitePlus
Y1137 Phosphorylation PhosphoSitePlus
T1144 Phosphorylation PhosphoSitePlus
Y1152 Phosphorylation PhosphoSitePlus
S1251 Phosphorylation PhosphoSitePlus
S1330 O-Glycosylation GlyGen 30379171
S1333 O-Glycosylation GlyGen 30379171
C1518 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
S367 Phosphorylation HPRD 18669648, 20068231
T605 Phosphorylation HPRD 15144186, 17924679


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S16 A16 Biomuta DOID:3571 / liver cancer [ cosmic ]
S222 L222 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S232 T232 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S301 C301 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S303 F303 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S450 C450 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K585 R585 Biomuta DOID:2531 / hematologic cancer [ cosmic ]