Protein Information

Cytoscape View

UniProt AC / UniProt ID O14791 / APOL1_HUMAN
Protein Name Apolipoprotein L1 precursor
Gene Name Name: APOL1
Organism Homo sapiens (Human)

PRO ID PR:O14791
DAG View
PRO Name apolipoprotein L1 (human)
Definition An apolipoprotein L1 that is encoded in the genome of human.
Short Label hAPOL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O14791 (APOL1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T59 O-Glycosylation GlyGen 30459171
K148 Ubiquitination PhosphoSitePlus
T236 O-Glycosylation PhosphoSitePlus
N261 N-Glycosylation GlyGen   UniProt 16335952
T307 Phosphorylation PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus   UniProt 26091039, 24275569
S314 Phosphorylation PhosphoSitePlus   UniProt 26091039, 24275569
Site PTM Type PTM Enzyme Score Source PMID
S311 Phosphorylation HPRD 19824718, 18702456, 20166139
S314 Phosphorylation HPRD 19824718, 20166139

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K148 E148 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
S311 A311 Biomuta DOID:263 / kidney cancer [ cosmic ]