Protein Information

Cytoscape View


UniProt AC / UniProt ID O14717 / TRDMT_HUMAN
Protein Name tRNA (cytosine(38)-C(5))-methyltransferase
Gene Name Name: TRDMT1
Synonyms:DNMT2;
Organism Homo sapiens (Human)

PRO ID PR:O14717
DAG View
PRO Name tRNA (cytosine(38)-C(5))-methyltransferase (human)
Definition A tRNA (cytosine-5-)-methyltransferase that is encoded in the genome of human.
Short Label hTRDMT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14717 (TRDMT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C24 Methylation IEDB 31844290
K122 Ubiquitination PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S153 P153 Biomuta DOID:3571 / liver cancer [ cosmic ]