iPTMnet Report for O14717 (TRDMT1)
Protein Information
UniProt AC / UniProt ID | O14717 / TRDMT_HUMAN |
Protein Name | tRNA (cytosine(38)-C(5))-methyltransferase |
Gene Name | Name: TRDMT1 Synonyms:DNMT2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O14717 |
PRO Name | tRNA (cytosine(38)-C(5))-methyltransferase (human) |
Definition | A tRNA (cytosine-5-)-methyltransferase that is encoded in the genome of human. |
Short Label | hTRDMT1 |
Category | organism-gene |
O14717 (TRDMT1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C24 | Methylation | score1 | IEDB | 31844290 | ||
K122 | Ubiquitination | score1 | PhosphoSitePlus | |||
S153 | Phosphorylation | score1 | PhosphoSitePlus | |||
K204 | Ubiquitination | score1 | PhosphoSitePlus | |||
K251 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S153 | P153 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |