iPTMnet Report for O14715 (RGPD8)
Protein Information
UniProt AC / UniProt ID | O14715 / RGPD8_HUMAN |
Protein Name | RANBP2-like and GRIP domain-containing protein 8 |
Gene Name | Name: RGPD8 Synonyms:RANBP2ALPHA,RANBP2L1,RANBP2L3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O14715 |
PRO Name | RANBP2-like and GRIP domain-containing protein 8 (human) |
Definition | A RANBP2-like and GRIP domain-containing protein 8 that is encoded in the genome of human. |
Short Label | hRGPD8 |
Category | organism-gene |
O14715 (RGPD8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T19 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
S21 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163 | ||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
K40 | Ubiquitination | score1 | PhosphoSitePlus | |||
S86 | Phosphorylation | score1 | PhosphoSitePlus | |||
T92 | Phosphorylation | score1 | PhosphoSitePlus | |||
K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
K99 | Ubiquitination | score1 | PhosphoSitePlus | |||
K106 | Ubiquitination | score1 | PhosphoSitePlus | |||
K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
S128 | Phosphorylation | score1 | PhosphoSitePlus | |||
K133 | Ubiquitination | score1 | PhosphoSitePlus | |||
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
S200 | Phosphorylation | score1 | PhosphoSitePlus | |||
S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
S261 | Phosphorylation | score1 | PhosphoSitePlus | |||
S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
K366 | Ubiquitination | score1 | PhosphoSitePlus | |||
K380 | Ubiquitination | score1 | PhosphoSitePlus | |||
K409 | Ubiquitination | score1 | PhosphoSitePlus | |||
T586 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y599 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y606 | Phosphorylation | score1 | PhosphoSitePlus | |||
K608 | Ubiquitination | score1 | PhosphoSitePlus | |||
K609 | Ubiquitination | score1 | PhosphoSitePlus | |||
K615 | Ubiquitination | score1 | PhosphoSitePlus | |||
K619 | Ubiquitination | score1 | PhosphoSitePlus | |||
K733 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y756 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y763 | Phosphorylation | score1 | PhosphoSitePlus | |||
K764 | Ubiquitination | score1 | PhosphoSitePlus | |||
S767 | Phosphorylation | score1 | PhosphoSitePlus | |||
S778 | Phosphorylation | score1 | PhosphoSitePlus | |||
T779 | Phosphorylation | score1 | PhosphoSitePlus | |||
S781 | Phosphorylation | score1 | PhosphoSitePlus | |||
K784 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y785 | Phosphorylation | score1 | PhosphoSitePlus | |||
S786 | Phosphorylation | score1 | PhosphoSitePlus | |||
S788 | Phosphorylation | score1 | PhosphoSitePlus | |||
S790 | Phosphorylation | score1 | PhosphoSitePlus | |||
K791 | Ubiquitination | score1 | PhosphoSitePlus | |||
S792 | Phosphorylation | score1 | PhosphoSitePlus | |||
K794 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y795 | Phosphorylation | score1 | PhosphoSitePlus | |||
S796 | Phosphorylation | score1 | PhosphoSitePlus | |||
T799 | Phosphorylation | score1 | PhosphoSitePlus | |||
T804 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
K823 | Ubiquitination | score1 | PhosphoSitePlus | |||
R890 | Methylation | score1 | PhosphoSitePlus | |||
T896 | Phosphorylation | score1 | PhosphoSitePlus | |||
K899 | Ubiquitination | score1 | PhosphoSitePlus | |||
K910 | Ubiquitination | score1 | PhosphoSitePlus | |||
S914 | Phosphorylation | score1 | PhosphoSitePlus | |||
S918 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 31492838, 30620550 | ||
S918 | Phosphorylation | score1 | PhosphoSitePlus | |||
K923 | Ubiquitination | score1 | PhosphoSitePlus | |||
S927 | Phosphorylation | score1 | PhosphoSitePlus | |||
K934 | Ubiquitination | score1 | PhosphoSitePlus | |||
T970 | Phosphorylation | score1 | PhosphoSitePlus | |||
S977 | Phosphorylation | score1 | PhosphoSitePlus | |||
T978 | Phosphorylation | score1 | PhosphoSitePlus | |||
S979 | Phosphorylation | score1 | PhosphoSitePlus | |||
K987 | Ubiquitination | score1 | PhosphoSitePlus | |||
K993 | Methylation | score1 | PhosphoSitePlus | |||
K993 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1016 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1017 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1027 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1029 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1032 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1046 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1057 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1065 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1085 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1094 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1120 | Ubiquitination | score1 | PhosphoSitePlus | |||
R1127 | Methylation | score1 | PhosphoSitePlus | |||
K1151 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1152 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1160 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1162 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1177 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1180 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1184 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1189 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1198 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1199 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1202 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1205 | Sumoylation | score1 | PhosphoSitePlus | |||
K1205 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1209 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1213 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1214 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1216 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1251 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1261 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1263 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1264 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1265 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1266 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1270 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1274 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1275 | Phosphorylation | P06493 (CDK1) | score1 | PhosphoSitePlus | 18234856 | |
S1294 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1300 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1302 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1303 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1304 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1368 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1374 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1382 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1390 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1403 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1411 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1415 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1420 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1422 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1439 | Acetylation | score1 | PhosphoSitePlus | |||
K1448 | Sumoylation | score1 | PhosphoSitePlus | |||
K1448 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1455 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1458 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1464 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1465 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1469 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1471 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1474 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1478 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1480 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1481 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1482 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1486 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1524 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1525 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1527 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1528 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1529 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1534 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1544 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1550 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1555 | Sumoylation | score1 | PhosphoSitePlus | |||
S1563 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1567 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1572 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1578 | Methylation | score1 | PhosphoSitePlus | |||
K1578 | Sumoylation | score1 | PhosphoSitePlus | |||
S1582 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1584 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1590 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1592 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1595 | Sumoylation | score1 | PhosphoSitePlus | |||
K1595 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1604 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1605 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1607 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1613 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1616 | Sumoylation | score1 | PhosphoSitePlus | |||
K1618 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1621 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1633 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1637 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1640 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1651 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1657 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1660 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1661 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1663 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1664 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1690 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1704 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1705 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1711 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1723 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1742 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1764 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S21 | L21 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K380 | R380 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S927 | L927 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K934 | N934 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S977 | L977 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
T1016 | S1016 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc, tcga ] | |
T1016 | N1016 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K1162 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T1184 | A1184 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S1261 | N1261 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K1368 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K1448 | N1448 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S1471 | Y1471 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S1486 | T1486 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S1550 | N1550 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] |