iPTMnet Report for O14682 (ENC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14682 / ENC1_HUMAN
Protein Name Ectoderm-neural cortex protein 1
Gene Name Name: ENC1
Synonyms:KLHL37,NRPB,PIG10;
Organism Homo sapiens (Human)

PRO ID PR:O14682
DAG View
PRO Name ectoderm-neural cortex protein 1 (human)
Definition An ectoderm-neural cortex protein 1 that is encoded in the genome of human.
Short Label hENC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14682 (ENC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
T46 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
S406 Phosphorylation IEDB   PhosphoSitePlus 27869121
Y417 Phosphorylation PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
K443 Ubiquitination PhosphoSitePlus
T452 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
S455 Phosphorylation PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
K527 Ubiquitination PhosphoSitePlus
T569 Phosphorylation PhosphoSitePlus
T570 Phosphorylation PhosphoSitePlus
Y573 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S435 Phosphorylation HPRD 17924679
S441 Phosphorylation HPRD 17924679
T569 Phosphorylation HPRD 18452278
T570 Phosphorylation HPRD 18452278
Y573 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y70 H70 Biomuta DOID:1324 / lung cancer [ cosmic ]
K423 N423 Biomuta DOID:4159 / skin cancer [ cosmic ]
T452 S452 Biomuta DOID:2394 / ovarian cancer [ cosmic ]