iPTMnet Report O14681 EI24

Protein Information

Cytoscape View

UniProt AC / UniProt ID	O14681 / EI24_HUMAN
Protein Name	Etoposide-induced protein 2.4 homolog
Gene Name	Name: EI24 Synonyms:PIG8;
Organism	Homo sapiens (Human)

PRO ID	PR:O14681 DAG View
PRO Name	etoposide-induced protein 2.4 homolog (human)
Definition	An etoposide-induced protein 2.4 that is encoded in the genome of human.
Short Label	hEI24
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

O14681 (EI24) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	A2	Acetylation		score1	UniProt	22814378
	K6	Ubiquitination		score1	PhosphoSitePlus
	K17	Ubiquitination		score1	PhosphoSitePlus
	S46	Phosphorylation		score1	PhosphoSitePlus
	S47	Phosphorylation		score1	PhosphoSitePlus
	S56	Phosphorylation		score2	PhosphoSitePlus UniProt	17081983, 20068231
	C264	Methylation		score1	IEDB	31844290
	S316	Phosphorylation		score1	PhosphoSitePlus
	S317	Phosphorylation		score1	PhosphoSitePlus
	T319	Phosphorylation		score1	PhosphoSitePlus
	S320	Phosphorylation		score1	PhosphoSitePlus
	K323	Ubiquitination		score1	PhosphoSitePlus
	S326	Phosphorylation		score2	PhosphoSitePlus UniProt	18691976, 18669648
	S330	Phosphorylation		score2	PhosphoSitePlus UniProt	18669648, 23186163, 24275569
	K335	Methylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S56	Phosphorylation		score0	HPRD	18691976, 17081983, 20068231
	S320	Phosphorylation		score0	HPRD	20058876
	S326	Phosphorylation		score0	HPRD	19413330, 18691976, 17081983, ...19664994, 19651622, 18669648, 20068231
	S330	Phosphorylation		score0	HPRD	19413330, 18691976, 17081983, ...19664994, 19651622, 18669648, 20068231

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T319	P319	Biomuta		DOID:2394 / ovarian cancer [ cosmic ]
S326	*	Biomuta		DOID:8618 / oral cavity cancer [ cosmic ]
S326	L326	Biomuta		DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]