iPTMnet Report for O14618 (CCS)
Protein Information
| UniProt AC / UniProt ID | O14618 / CCS_HUMAN |
| Protein Name | Copper chaperone for superoxide dismutase |
| Gene Name | Name: CCS |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O14618 |
| PRO Name | copper chaperone for superoxide dismutase (human) |
| Definition | A copper chaperone for superoxide dismutase that is encoded in the genome of human. |
| Short Label | hCCS |
| Category | organism-gene |
DAG ViewO14618 (CCS) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K76 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 20154138 | ||
| T109 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R165 | Methylation | score1 | PhosphoSitePlus | |||
| K189 | Ubiquitination | score2 | UniProt | 20154138 | ||
| R209 | Methylation | score1 | PhosphoSitePlus | |||
| K216 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 20154138 | ||
| K241 | Ubiquitination | score2 | UniProt | 20154138 | ||
| S267 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 20166139, 17287340, 24275569 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T109 | S109 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| K216 | N216 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
