iPTMnet Report for O14617 (AP3D1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14617 / AP3D1_HUMAN
Protein Name AP-3 complex subunit delta-1
Gene Name Name: AP3D1
ORFNames:PRO0039;
Organism Homo sapiens (Human)

PRO ID PR:O14617
DAG View
PRO Name AP-3 complex subunit delta-1 (human)
Definition An AP-3 complex subunit delta-1 that is encoded in the genome of human.
Short Label hAP3D1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14617 (AP3D1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K4 Ubiquitination PhosphoSitePlus
K7 Ubiquitination PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
C60 Methylation IEDB 31844290
K164 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K176 Acetylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
C208 Methylation IEDB 31844290
T230 Phosphorylation IEDB 35494241
T270 Phosphorylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
Y365 Phosphorylation PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K386 Acetylation PhosphoSitePlus
C479 Methylation IEDB 31844290
K584 Ubiquitination PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
K610 Ubiquitination PhosphoSitePlus
K613 Ubiquitination PhosphoSitePlus
S632 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18669648, ...24275569, 20068231
S634 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 18669648, 17081983, ...24275569
S636 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 18669648, 17081983, ...24275569
S658 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 17081983
K673 Ubiquitination PhosphoSitePlus
Y682 Phosphorylation PhosphoSitePlus
S685 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S686 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S688 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T696 Phosphorylation PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus
Y724 Phosphorylation PhosphoSitePlus
K736 Acetylation PhosphoSitePlus
S758 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S759 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T762 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S764 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T778 Phosphorylation PhosphoSitePlus
A785 Phosphorylation UniProt 24275569
S788 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 24275569, ...17081983
Y799 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K808 Ubiquitination PhosphoSitePlus
K820 Ubiquitination PhosphoSitePlus
T824 Phosphorylation PhosphoSitePlus
T826 Phosphorylation PhosphoSitePlus
S827 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K828 Phosphorylation UniProt 18669648
S829 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 18088087, ...20068231
S869 Phosphorylation phospho.ELM 18669648
V931 Phosphorylation UniProt 18669648
S1043 Phosphorylation IEDB 32387766
S1070 Phosphorylation PhosphoSitePlus
S1071 Phosphorylation PhosphoSitePlus
C1089 Methylation IEDB 31844290
C1103 Methylation IEDB 31844290
C1103 S-Nitrosylation dbSNO 26338901
K1132 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S369 Phosphorylation HPRD 20068231
S632 Phosphorylation HPRD 19651622, 18669648, 20068231
S634 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S636 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S658 Phosphorylation HPRD 19651622, 20166139, 20068231
S685 Phosphorylation HPRD 18669648
S686 Phosphorylation HPRD 18669648
S688 Phosphorylation HPRD 18669648
S721 Phosphorylation HPRD 19413330
S758 Phosphorylation HPRD 18669648, 17081983, 20068231
S759 Phosphorylation HPRD 18669648, 17081983, 20068231
T762 Phosphorylation HPRD 18669648, 17081983, 20068231
S764 Phosphorylation HPRD 18669648, 17081983, 20068231
T778 Phosphorylation HPRD 20058876, 17081983
S788 Phosphorylation HPRD 18669648, 20058876, 17081983, ...20068231
Y799 Phosphorylation HPRD 18669648, 17081983
T824 Phosphorylation HPRD 17081983
T826 Phosphorylation HPRD 19664995, 20068231
S827 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 19664995
S829 Phosphorylation HPRD 19651622, 18669648, 18088087, ...20068231, 18707149
T1032 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S785 Phosphorylation PhosphoSitePlus
T787 Phosphorylation PhosphoSitePlus
S828 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K386 Acetylation PhosphoSitePlus
S632 Phosphorylation phospho.ELM 18669648
S634 Phosphorylation phospho.ELM 18669648
S636 Phosphorylation phospho.ELM 18669648
S685 Phosphorylation phospho.ELM 18669648
S686 Phosphorylation phospho.ELM 18669648
S688 Phosphorylation phospho.ELM 18669648
S758 Phosphorylation phospho.ELM 18669648
S759 Phosphorylation phospho.ELM 18669648
T762 Phosphorylation phospho.ELM 18669648
S764 Phosphorylation phospho.ELM 18669648
S788 Phosphorylation phospho.ELM 18669648
Y799 Phosphorylation phospho.ELM 18669648
S827 Phosphorylation phospho.ELM 18669648
S829 Phosphorylation phospho.ELM 18669648
T878 Phosphorylation PhosphoSitePlus
S897 Phosphorylation PhosphoSitePlus
S931 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K191 N191 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T230 M230 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T270 M270 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S369 F369 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K610 N610 Biomuta DOID:1319 / brain cancer [ icgc ]
K610 M610 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S632 L632 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S686 L686 Biomuta [ cosmic ]
S688 L688 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
A785 V785 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S788 N788 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S827 L827 Biomuta DOID:1324 / lung cancer [ cosmic ]
S827 P827 Biomuta DOID:184 / bone cancer [ cosmic ]
K828 E828 Biomuta DOID:363 / uterine cancer [ cosmic ]
S829 F829 Biomuta [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:184 / bone cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic ]
T1032 N1032 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1071 L1071 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]