iPTMnet Report for O14594 (NCAN)
Protein Information
| UniProt AC / UniProt ID | O14594 / NCAN_HUMAN |
| Protein Name | Neurocan core protein precursor |
| Gene Name | Name: NCAN Synonyms:CSPG3,NEUR; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O14594 |
| PRO Name | neurocan core protein (human) |
| Definition | A neurocan core protein that is encoded in the genome of human. |
| Short Label | hNCAN |
| Category | organism-gene |
DAG ViewO14594 (NCAN) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N122 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| T124 | O-Glycosylation | score1 | GlyGen | 28657654 | ||
| S381 | O-Glycosylation | score2 | GlyGen UniProt | 25326458 | ||
| S411 | O-Glycosylation | score2 | GlyGen UniProt | 25326458 | ||
| S539 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20166139 | ||
| T545 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20166139 | ||
| S725 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T871 | O-Glycosylation | score1 | GlyGen | 30459171 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N122 | K122 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| N122 | I122 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S411 | G411 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S725 | I725 | Biomuta | [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
| T871 | M871 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] |
