iPTMnet Report for O14576 (DYNC1I1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14576 / DC1I1_HUMAN
Protein Name Cytoplasmic dynein 1 intermediate chain 1
Gene Name Name: DYNC1I1
Synonyms:DNCI1,DNCIC1;
Organism Homo sapiens (Human)

PRO ID PR:O14576
DAG View
PRO Name cytoplasmic dynein 1 intermediate chain 1 (human)
Definition A cytoplasmic dynein 1 intermediate chain 1 that is encoded in the genome of human.
Short Label hDYNC1I1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14576 (DYNC1I1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Acetylation PhosphoSitePlus
K8 Acetylation PhosphoSitePlus
K14 Acetylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
T105 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
T154 O-Glycosylation GlyGen 28657654
S165 Phosphorylation PhosphoSitePlus
T176 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
C394 Methylation IEDB 31844290
T408 Phosphorylation IEDB 32387766
S635 Phosphorylation PhosphoSitePlus   UniProt 19690332
Site PTM Type PTM Enzyme Score Source PMID
T176 Phosphorylation HPRD 18510355
Site PTM Type PTM Enzyme Score Source PMID
S80 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S80 P80 Biomuta DOID:4159 / skin cancer [ cosmic ]
S104 N104 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T105 P105 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T154 P154 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T154 I154 Biomuta DOID:363 / uterine cancer [ icgc ]
S165 F165 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T176 M176 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ icgc ]
S635 G635 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]