iPTMnet Report for O14559 (ARHGAP33)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14559 / RHG33_HUMAN
Protein Name Rho GTPase-activating protein 33
Gene Name Name: ARHGAP33
Synonyms:SNX26,TCGAP;
Organism Homo sapiens (Human)

PRO ID PR:O14559
DAG View
PRO Name Rho GTPase-activating protein 33 (human)
Definition A Rho GTPase-activating protein 33 that is encoded in the genome of human.
Short Label hARHGAP33
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14559 (ARHGAP33) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S67 O-Glycosylation GlyGen 30379171, 29351928
S74 O-Glycosylation GlyGen 30379171, 29351928
S178 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
Y197 Phosphorylation PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
Y406 Phosphorylation P06241 (FYN) PhosphoSitePlus   Signor 16777849
S532 Phosphorylation PhosphoSitePlus
T552 Phosphorylation PhosphoSitePlus
T558 Phosphorylation PhosphoSitePlus
T560 Phosphorylation PhosphoSitePlus
T564 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
T593 O-Glycosylation GlyGen 30379171, 29351928
S624 Phosphorylation PhosphoSitePlus
T628 Phosphorylation PhosphoSitePlus
T630 Phosphorylation PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus   UniProt 21406692
S780 Phosphorylation PhosphoSitePlus
S955 O-Glycosylation GlyGen 30379171, 29351928
S978 O-Glycosylation GlyGen 30379171, 29351928
S1125 Phosphorylation PhosphoSitePlus
Y1169 Phosphorylation PhosphoSitePlus
R1194 Methylation PhosphoSitePlus
R1244 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y406 Phosphorylation P06241 (FYN) HPRD 16777849
T552 Phosphorylation HPRD 18077418
T558 Phosphorylation HPRD 18077418
T560 Phosphorylation HPRD 18077418


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y406 C406 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T558 M558 Biomuta DOID:1725 / peritoneum cancer [ cosmic ]
T560 M560 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]