iPTMnet Report for O14531 (DPYSL4)
Protein Information
| UniProt AC / UniProt ID | O14531 / DPYL4_HUMAN |
| Protein Name | Dihydropyrimidinase-related protein 4 |
| Gene Name | Name: DPYSL4 Synonyms:CRMP3,ULIP4; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O14531 |
| PRO Name | dihydropyrimidinase-related protein 4 (human) |
| Definition | A dihydropyrimidinase-related protein 4 that is encoded in the genome of human. |
| Short Label | hDPYSL4 |
| Category | organism-gene |
O14531 (DPYSL4) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Phosphorylation | score1 | PRO | ||||
| K258 | Acetylation | score1 | PhosphoSitePlus | |||
| K268 | Acetylation | score1 | PhosphoSitePlus | |||
| K268 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S292 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T473 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K480 | Acetylation | score1 | PhosphoSitePlus | |||
| R496 | Methylation | score1 | PhosphoSitePlus | |||
| S544 | Phosphorylation | score2 | HPRD phospho.ELM PRO PhosphoSitePlus | 17525332 | ||
| T569 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S570 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S572 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000047210 (hDPYSL4/Phos:1) | pS544 | PRO | |||
| PR:000047211 (hDPYSL4/PhosTyr+) | p | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T473 | K473 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| R496 | S496 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| R496 | H496 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
DAG View