iPTMnet Report for O14526 (FCHO1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14526 / FCHO1_HUMAN
Protein Name F-BAR domain only protein 1
Gene Name Name: FCHO1
Synonyms:KIAA0290;
Organism Homo sapiens (Human)

PRO ID PR:O14526
DAG View
PRO Name F-BAR domain only protein 1 (human)
Definition An F-BAR domain only protein 1 that is encoded in the genome of human.
Short Label hFCHO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14526 (FCHO1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y20 Phosphorylation PhosphoSitePlus
T30 Phosphorylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K80 Acetylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
Y141 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus   UniProt 23186163
S347 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y358 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus   UniProt 23186163
S386 Phosphorylation PhosphoSitePlus
T396 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
S523 Phosphorylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
S530 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
S583 Phosphorylation PhosphoSitePlus
S585 Phosphorylation PhosphoSitePlus
S587 Phosphorylation PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus   UniProt 19690332
T652 Phosphorylation PhosphoSitePlus
T808 Phosphorylation PhosphoSitePlus
K814 Ubiquitination PhosphoSitePlus
T817 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y141 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y20 D20 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T30 A30 Biomuta DOID:363 / uterine cancer [ icgc ]
K80 T80 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K97 Q97 Biomuta DOID:10283 / prostate cancer [ icgc ]
Y141 C141 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K262 T262 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S347 F347 Biomuta DOID:1319 / brain cancer [ cosmic ]
S612 F612 Biomuta DOID:4159 / skin cancer [ cosmic ]
S612 Y612 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]