iPTMnet Report for O14522 (PTPRT)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14522 / PTPRT_HUMAN
Protein Name Receptor-type tyrosine-protein phosphatase T precursor
Gene Name Name: PTPRT
Synonyms:KIAA0283;
Organism Homo sapiens (Human)

PRO ID PR:O14522
DAG View
PRO Name receptor-type tyrosine-protein phosphatase T (human)
Definition A receptor-type tyrosine-protein phosphatase T that is encoded in the genome of human.
Short Label hPTPRT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14522 (PTPRT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y107 Phosphorylation PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
T251 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
T404 Phosphorylation PhosphoSitePlus
Y412 Phosphorylation PhosphoSitePlus
T415 Phosphorylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus
S728 Phosphorylation PhosphoSitePlus
T767 Phosphorylation PhosphoSitePlus
S1208 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T240 Phosphorylation PhosphoSitePlus
T763 Phosphorylation PhosphoSitePlus
T786 Phosphorylation PhosphoSitePlus
Y915 Phosphorylation P06241 (FYN) PhosphoSitePlus 19816407
Y1030 Phosphorylation P06241 (FYN) PhosphoSitePlus 19816407
Y1351 Phosphorylation PhosphoSitePlus
Y1359 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y108 * Biomuta DOID:1324 / lung cancer [ tcga ]
S249 L249 Biomuta DOID:1612 / breast cancer [ cosmic ]
S261 R261 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y412 * Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S537 R537 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:1324 / lung cancer [ cosmic, tcga ] DOID:0070003 / blastoma [ cosmic ]
T767 I767 Biomuta DOID:363 / uterine cancer [ tcga ]