iPTMnet Report for O14508 (SOCS2)
Protein Information
| UniProt AC / UniProt ID | O14508 / SOCS2_HUMAN |
| Protein Name | Suppressor of cytokine signaling 2 |
| Gene Name | Name: SOCS2 Synonyms:CIS2,SSI2,STATI2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O14508 |
| PRO Name | suppressor of cytokine signaling 2 (human) |
| Definition | A suppressor of cytokine signaling 2 that is encoded in the genome of human. |
| Short Label | hSOCS2 |
| Category | organism-gene |
DAG ViewO14508 (SOCS2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C5 | S-Nitrosylation | score0 | dbSNO | 24105792 | ||
| S30 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S52 | Phosphorylation | score2 | UniProt | 31578312 | ||
| C111 | S-Nitrosylation | score0 | dbSNO | 22178444 | ||
| C167 | S-Nitrosylation | score0 | dbSNO | 24105792 | ||
| K173 | Ubiquitination | score2 | UniProt | 31578312 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S52 | G52 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S52 | I52 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| C111 | Y111 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| C167 | R167 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
