iPTMnet Report for O08553 (Dpysl2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O08553 / DPYL2_MOUSE
Protein Name Dihydropyrimidinase-related protein 2
Gene Name Name: Dpysl2
Synonyms:Crmp2,Ulip2;
Organism Mus musculus (Mouse)

PRO ID PR:O08553
DAG View
PRO Name dihydropyrimidinase-related protein 2 (mouse)
Definition A dihydropyrimidinase-related protein 2 that is encoded in the genome of mouse.
Short Label mDPYSL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O08553 (Dpysl2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Ubiquitination PhosphoSitePlus
K7 Ubiquitination PhosphoSitePlus
T13 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
K20 Ubiquitination PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
Y32 Phosphorylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
T177 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
T241 O-Glycosylation GlyGen 28657654
C248 S-Nitrosylation dbSNO 19101475, 21278135, 22588120, ...22865876, 24895380
K293 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
K368 Ubiquitination PhosphoSitePlus
K374 Sumoylation PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus   UniProt 21183079
S405 Phosphorylation PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
Y431 Phosphorylation PhosphoSitePlus   UniProt 18034455
C439 S-Nitrosylation dbSNO 22865876, 21278135, 24895380
S442 Phosphorylation PhosphoSitePlus
T458 Phosphorylation PhosphoSitePlus
S465 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15648052
K472 Ubiquitination PhosphoSitePlus
K480 Acetylation PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
Y499 Phosphorylation PhosphoSitePlus   UniProt 18034455
C504 S-Nitrosylation dbSNO 28493997, 19101475, 24441547, ...22588120, 26702143, 24895380
S507 O-Glycosylation GlyGen   PhosphoSitePlus 31771416, 28528544, 32848054, ...30031227, 33300544, 34678516, 25153642, 22517741, 36288343, 22645316, 35822049
S507 Phosphorylation PhosphoSitePlus   UniProt 21183079
T509 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 28638064, 15676027, 29758318, ...16452087, 16611631, 21183079, 16230462, 17114649, 18034455, 35589915, 15345747, 32049584
T509 Phosphorylation Q9WV60 (Gsk3b) PhosphoSitePlus 16611631
K511 Ubiquitination PhosphoSitePlus
T512 O-Glycosylation GlyGen 32848054, 28657654
T512 Phosphorylation PhosphoSitePlus   UniProt 21183079
T514 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 31771416, 28524835, 28638064, ...23470087, 32019603, 26250894, 29758318, 16230462, 16452087, 16611631, 21183079, 19131326, 29434807, 30046097, 32848595, 31453382, 22057101, 32049584, 25073924, 36293516
T514 Phosphorylation Q9WV60 (Gsk3b) PhosphoSitePlus 16611631
S517 O-Glycosylation GlyGen 31771416, 34678516, 28528544, ...30031227, 33300544, 25153642, 22517741, 36288343, 22645316, 35822049
S517 Phosphorylation PhosphoSitePlus   UniProt 21183079, 19131326
S518 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21183079, 19131326, 32848595, ...28638064
K520 Ubiquitination PhosphoSitePlus
T521 Phosphorylation PhosphoSitePlus   UniProt 21183079
S522 Phosphorylation IntAct   PhosphoSitePlus   RLIMS-P+   RLIMS-P   UniProt 31771416, 33318403, 21943307, ...22279220, 32019603, 29758318, 16230462, 15676027, 30194029, 21183079, 19131326, 30375127, 23022559, 32848595, 17683481
S522 Phosphorylation P49615 (Cdk5) RLIMS-P+ 15676027
K525 Ubiquitination PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus   UniProt 21183079
S540 Phosphorylation PhosphoSitePlus   UniProt 21183079
S542 Phosphorylation PhosphoSitePlus   UniProt 21183079
T554 Phosphorylation PhosphoSitePlus
T555 Phosphorylation PhosphoSitePlus   RLIMS-P 22544872, 24227739, 32019603, ...32848595, 32860158
T555 Phosphorylation P05132 (Prkaca) PhosphoSitePlus 24227739
R565 Methylation PhosphoSitePlus   UniProt 24129315
T569 O-Glycosylation GlyGen 32848054
S570 O-Glycosylation GlyGen 34678516, 32848054


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O08553 (Dpysl2) T514 O35964 (Sh3gl1) unknown eFIP 32848595