iPTMnet Report for O00746 (NME4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00746 / NDKM_HUMAN
Protein Name Nucleoside diphosphate kinase, mitochondrial precursor
Gene Name Name: NME4
Synonyms:NM23D;
Organism Homo sapiens (Human)

PRO ID PR:O00746
DAG View
PRO Name nucleoside diphosphate kinase, mitochondrial (human)
Definition A nucleoside diphosphate kinase, mitochondrial that is encoded in the genome of human.
Short Label hNME4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00746 (NME4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation PhosphoSitePlus
T36 Phosphorylation PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
K91 Acetylation PhosphoSitePlus
Y100 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T127 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y114 H114 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T127 I127 Biomuta DOID:4159 / skin cancer [ cosmic ]
S153 N153 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]