iPTMnet Report O00712 NFIB

Protein Information

UniProt AC / UniProt ID	O00712 / NFIB_HUMAN
Protein Name	Nuclear factor 1 B-type
Gene Name	Name: NFIB
Organism	Homo sapiens (Human)

PRO ID	PR:O00712 DAG View
PRO Name	nuclear factor 1 B-type (human)
Definition	A nuclear factor 1 B-type that is encoded in the genome of human.
Short Label	hNFIB
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

O00712 (NFIB) as Substrate

Condensed View

Site	PTM Type	Score	Source	PMID
S4	Phosphorylation	score1	PhosphoSitePlus
S50	Phosphorylation	score1	PhosphoSitePlus
K58	Ubiquitination	score1	PhosphoSitePlus
S63	Phosphorylation	score1	PhosphoSitePlus
K65	Ubiquitination	score1	PhosphoSitePlus
K100	Ubiquitination	score1	PhosphoSitePlus
K112	Ubiquitination	score1	PhosphoSitePlus
T146	Phosphorylation	score1	PhosphoSitePlus
S194	Phosphorylation	score1	PhosphoSitePlus
S196	Phosphorylation	score1	PhosphoSitePlus
Y207	Phosphorylation	score1	PhosphoSitePlus
S211	Phosphorylation	score1	PhosphoSitePlus
K214	Ubiquitination	score1	PhosphoSitePlus
S221	Phosphorylation	score1	PhosphoSitePlus
S246	Phosphorylation	score1	PhosphoSitePlus
S262	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18669648
S264	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	18669648
S265	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18669648
S268	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18669648
S269	Phosphorylation	score1	PhosphoSitePlus
S276	Phosphorylation	score1	PhosphoSitePlus
S284	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18669648
T286	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18669648
Y290	Phosphorylation	score1	PhosphoSitePlus
S292	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 24275569
S294	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18669648
S295	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 24275569
S312	Phosphorylation	score2	PhosphoSitePlus UniProt	23186163, 20068231
T314	Phosphorylation	score1	PhosphoSitePlus
S325	O-Glycosylation	score3	GlyGen	33214551, 31492838, 35254053, ...34019948, 17511965, 35289036
S325	Phosphorylation	score1	PhosphoSitePlus
S326	O-Glycosylation	score3	GlyGen	33214551, 31492838, 35254053, ...34019948, 17511965, 35289036
S326	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18669648
S328	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 23186163, 20068231
S332	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18669648
S333	O-Glycosylation	score3	GlyGen	33214551, 31492838, 35254053, ...34019948, 17511965, 35289036
S333	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 23186163, 20068231
R335	Methylation	score1	PhosphoSitePlus
T359	Phosphorylation	score1	PhosphoSitePlus
S364	Phosphorylation	score1	PhosphoSitePlus
R388	Methylation	score1	PhosphoSitePlus
K400	Methylation	score1	PhosphoSitePlus
S410	Phosphorylation	score1	PhosphoSitePlus
T413	Phosphorylation	score1	phospho.ELM	18669648
S416	O-Glycosylation	score3	GlyGen	33214551, 31492838, 35254053, ...34019948, 17511965, 35289036

Site	PTM Type	Score	Source	PMID
Y3	Phosphorylation	score0	HPRD	20068231
S50	Phosphorylation	score0	HPRD	20068231
S63	Phosphorylation	score0	HPRD	20068231
S262	Phosphorylation	score0	HPRD	18669648
S264	Phosphorylation	score0	HPRD	18669648
S265	Phosphorylation	score0	HPRD	18669648
S268	Phosphorylation	score0	HPRD	18669648
S276	Phosphorylation	score0	HPRD	18452278
S284	Phosphorylation	score0	HPRD	18669648, 20068231, 18452278
T286	Phosphorylation	score0	HPRD	18669648, 18452278
S292	Phosphorylation	score0	HPRD	18669648, 20068231, 18452278
S294	Phosphorylation	score0	HPRD	18669648, 20068231, 18452278
S295	Phosphorylation	score0	HPRD	18669648, 15345747, 20068231, ...18452278
S300	Phosphorylation	score0	HPRD	18452278
S312	Phosphorylation	score0	HPRD	20068231
T314	Phosphorylation	score0	HPRD	20068231
S325	Phosphorylation	score0	HPRD	20068231
S326	Phosphorylation	score0	HPRD	18669648
S328	Phosphorylation	score0	HPRD	18669648, 20068231, 18452278
S332	Phosphorylation	score0	HPRD	18669648, 20068231
S333	Phosphorylation	score0	HPRD	18669648, 20068231
S409	Phosphorylation	score0	HPRD	20068231
S410	Phosphorylation	score0	HPRD	20068231
T413	Phosphorylation	score0	HPRD	20068231

Site	PTM Type	Score	Source
S410	Phosphorylation	score1	PhosphoSitePlus
T413	Phosphorylation	score1	PhosphoSitePlus
S414	Phosphorylation	score1	PhosphoSitePlus
T431	Phosphorylation	score1	PhosphoSitePlus
S437	Phosphorylation	score1	PhosphoSitePlus
S478	Phosphorylation	score1	PhosphoSitePlus

Site	PTM Type	Score	Source
S158	Phosphorylation	score1	PhosphoSitePlus
T179	Phosphorylation	score1	PhosphoSitePlus
S185	Phosphorylation	score1	PhosphoSitePlus
S226	Phosphorylation	score1	PhosphoSitePlus
S308	Phosphorylation	score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	Disease [Sample source]
S4	F4	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S50	P50	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
K112	N112	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
S158	I158	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
S194	R194	Biomuta	DOID:1612 / breast cancer [ cosmic, icgc ]
S211	N211	Biomuta	DOID:363 / uterine cancer [ icgc ]
S262	Y262	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
S269	G269	Biomuta	DOID:1319 / brain cancer [ cosmic, icgc ]
S269	R269	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T286	I286	Biomuta	DOID:1612 / breast cancer [ icgc ]
S292	Y292	Biomuta	DOID:1319 / brain cancer [ icgc ]
S295	P295	Biomuta	DOID:9256 / colorectal cancer [ icgc ]
S332	F332	Biomuta	DOID:9256 / colorectal cancer [ cosmic, icgc ]
S332	Y332	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S333	F333	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
S410	I410	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
T413	I413	Biomuta	DOID:10534 / stomach cancer [ cosmic, icgc ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for O00712 (NFIB)

Protein Information

Interactive Sequence View

O00712 (NFIB) as Substrate

PTM sites affected in variants