iPTMnet Report for O00635 (TRIM38)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00635 / TRI38_HUMAN
Protein Name E3 ubiquitin-protein ligase TRIM38
Gene Name Name: TRIM38
Synonyms:RNF15,RORET;
Organism Homo sapiens (Human)

PRO ID PR:O00635
DAG View
PRO Name E3 ubiquitin-protein ligase TRIM38 (human)
Definition An E3 ubiquitin-protein ligase TRIM38 that is encoded in the genome of human.
Short Label hTRIM38
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00635 (TRIM38) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K50 Ubiquitination PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus   UniProt 24275569
K75 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
T155 O-Glycosylation GlyGen 30379171, 28510447
K158 Ubiquitination PhosphoSitePlus
K167 Acetylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
T319 Phosphorylation PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S70 C70 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S70 N70 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K158 E158 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K243 R243 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K375 N375 Biomuta DOID:363 / uterine cancer [ icgc ]