iPTMnet Report for O00635 (TRIM38)
Protein Information
UniProt AC / UniProt ID | O00635 / TRI38_HUMAN |
Protein Name | E3 ubiquitin-protein ligase TRIM38 |
Gene Name | Name: TRIM38 Synonyms:RNF15,RORET; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O00635 |
PRO Name | E3 ubiquitin-protein ligase TRIM38 (human) |
Definition | An E3 ubiquitin-protein ligase TRIM38 that is encoded in the genome of human. |
Short Label | hTRIM38 |
Category | organism-gene |
O00635 (TRIM38) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K50 | Ubiquitination | score1 | PhosphoSitePlus | |||
S70 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
K75 | Ubiquitination | score1 | PhosphoSitePlus | |||
K122 | Ubiquitination | score1 | PhosphoSitePlus | |||
K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
K142 | Ubiquitination | score1 | PhosphoSitePlus | |||
K148 | Ubiquitination | score1 | PhosphoSitePlus | |||
T155 | O-Glycosylation | score1 | GlyGen | 30379171, 28510447 | ||
K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
K167 | Acetylation | score1 | PhosphoSitePlus | |||
K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
K203 | Ubiquitination | score1 | PhosphoSitePlus | |||
K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
K236 | Ubiquitination | score1 | PhosphoSitePlus | |||
K243 | Ubiquitination | score1 | PhosphoSitePlus | |||
K284 | Ubiquitination | score1 | PhosphoSitePlus | |||
T319 | Phosphorylation | score1 | PhosphoSitePlus | |||
K375 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S70 | C70 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S70 | N70 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K158 | E158 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K243 | R243 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
K375 | N375 | Biomuta | DOID:363 / uterine cancer [ icgc ] |