Protein Information

Cytoscape View

UniProt AC / UniProt ID O00629 / IMA3_HUMAN
Protein Name Importin subunit alpha-3
Gene Name Name: KPNA4
Organism Homo sapiens (Human)

PRO ID PR:O00629
DAG View
PRO Name importin subunit alpha-3 (human)
Definition An importin subunit alpha-3 that is encoded in the genome of human.
Short Label hKPNA4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O00629 (KPNA4) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
K6 Ubiquitination PhosphoSitePlus
T24 Phosphorylation PhosphoSitePlus
R26 Methylation PhosphoSitePlus
R37 Methylation PhosphoSitePlus
S60 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 17081983, 31822798, ...18669648, 24275569, 19690332, 20068231
Y66 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T71 Phosphorylation HPRD 20068231
K97 Acetylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
R103 Methylation PhosphoSitePlus
T221 Phosphorylation PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
Y474 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:363 / uterine cancer [ tcga ]
R103 Q103 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]