Protein Information

Cytoscape View

UniProt AC / UniProt ID O00625 / PIR_HUMAN
Protein Name Pirin
Gene Name Name: PIR
Organism Homo sapiens (Human)

PRO ID PR:O00625
DAG View
PRO Name pirin (human)
Definition A pirin that is encoded in the genome of human.
Short Label hPIR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O00625 (PIR) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T8 O-Glycosylation PhosphoSitePlus
T8 Phosphorylation HPRD 20068231
S17 Phosphorylation PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
R97 Methylation PhosphoSitePlus
Y131 Phosphorylation PhosphoSitePlus
K135 Sumoylation PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
K175 Acetylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
K234 Acetylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K135 E135 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K275 T275 Biomuta DOID:1793 / pancreatic cancer [ tcga ]