iPTMnet Report for O00625 (PIR)
Protein Information
| UniProt AC / UniProt ID | O00625 / PIR_HUMAN |
| Protein Name | Pirin |
| Gene Name | Name: PIR |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O00625 |
| PRO Name | pirin (human) |
| Definition | A pirin that is encoded in the genome of human. |
| Short Label | hPIR |
| Category | organism-gene |
DAG ViewO00625 (PIR) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T8 | O-Glycosylation | score1 | PhosphoSitePlus | |||
| T8 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R97 | Methylation | score1 | PhosphoSitePlus | |||
| C106 | Methylation | score1 | IEDB | 31844290 | ||
| Y131 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K135 | Sumoylation | score1 | PhosphoSitePlus | |||
| S161 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K175 | Acetylation | score1 | PhosphoSitePlus | |||
| K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K234 | Acetylation | score1 | PhosphoSitePlus | |||
| K275 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S17 | L17 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K135 | E135 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K234 | N234 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| K275 | T275 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] |
