Protein Information

Cytoscape View


UniProt AC / UniProt ID O00567 / NOP56_HUMAN
Protein Name Nucleolar protein 56
Gene Name Name: NOP56
Synonyms:NOL5A;
Organism Homo sapiens (Human)

PRO ID PR:O00567
DAG View
PRO Name nucleolar protein 56 (human)
Definition A nucleolar protein 56 that is encoded in the genome of human.
Short Label hNOP56
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00567 (NOP56) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K41 Ubiquitination PhosphoSitePlus
T82 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K143 Methylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
K156 Acetylation PhosphoSitePlus
K158 Acetylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
Y195 Phosphorylation PhosphoSitePlus
Y210 Phosphorylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
Y277 Phosphorylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
S295 Phosphorylation HPRD 20068231
S297 Phosphorylation HPRD 20068231
S314 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
T316 Phosphorylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
K333 Acetylation PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
R359 Methylation PhosphoSitePlus   UniProt 24129315
S369 Phosphorylation HPRD   PhosphoSitePlus 20068231
K375 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
R404 Methylation PhosphoSitePlus
S406 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16565220
K416 Ubiquitination PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
S466 Phosphorylation HPRD   PhosphoSitePlus 19413330
S467 Phosphorylation HPRD   PhosphoSitePlus 19413330
T468 Phosphorylation HPRD   PhosphoSitePlus 19413330
S476 Phosphorylation PhosphoSitePlus
K478 Methylation PhosphoSitePlus
K480 Methylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
S502 Phosphorylation PhosphoSitePlus
S511 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 20068231
S513 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K514 Ubiquitination PhosphoSitePlus
S519 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 23186163, ...17081983, 18767875, 18452278, 19651622, 18669648, 19690332, 20068231
S520 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 18578522, ...23186163, 17081983, 18767875, 20058876, 19691289, 16565220, 19651622, 18669648, 19415658, 24275569, 18707149, 18452278, 19690332, 20068231
T525 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 19691289, 20068231
S528 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S530 Phosphorylation PhosphoSitePlus
S537 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T538 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K540 Sumoylation PhosphoSitePlus
T543 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S554 Phosphorylation PhosphoSitePlus
S556 Phosphorylation HPRD   PhosphoSitePlus 20068231
S563 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20166139, 23186163, 24275569, ...18707149
S569 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 19651622, 23186163, ...19690332
S570 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...20058876, 19651622, 18669648, 18707149
S579 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S580 Phosphorylation PhosphoSitePlus
S581 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S591 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S295 N295 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S297 * Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
R359 Q359 Biomuta DOID:10534 / stomach cancer [ tcga ]
R404 * Biomuta DOID:363 / uterine cancer [ cosmic, tcga ] DOID:10534 / stomach cancer [ icgc, tcga ]
S467 N467 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K478 T478 Biomuta DOID:1909 / melanoma [ cosmic ]
S511 Y511 Biomuta DOID:363 / uterine cancer [ icgc, tcga ]
T538 A538 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S569 I569 Biomuta DOID:5041 / esophageal cancer [ tcga ]
S579 R579 Biomuta DOID:2394 / ovarian cancer [ tcga ]
S581 F581 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]