iPTMnet Report for O00562 (PITPNM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00562 / PITM1_HUMAN
Protein Name Membrane-associated phosphatidylinositol transfer protein 1
Gene Name Name: PITPNM1
Synonyms:DRES9,NIR2,PITPNM;
Organism Homo sapiens (Human)

PRO ID PR:O00562
DAG View
PRO Name membrane-associated phosphatidylinositol transfer protein 1 (human)
Definition A membrane-associated phosphatidylinositol transfer protein 1 that is encoded in the genome of human.
Short Label hPITPNM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00562 (PITPNM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T59 Phosphorylation PhosphoSitePlus   UniProt 12225667
C101 Methylation IEDB 31844290
K166 Ubiquitination PhosphoSitePlus
S173 Phosphorylation IEDB 35494241
T287 Phosphorylation P06493 (CDK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 15125835
S300 Phosphorylation PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
S382 Phosphorylation P06493 (CDK1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15125835
T389 Phosphorylation phospho.ELM   PhosphoSitePlus 15125835
S509 Phosphorylation PhosphoSitePlus
Y528 Phosphorylation PhosphoSitePlus
S593 Phosphorylation PhosphoSitePlus
S600 Phosphorylation PhosphoSitePlus   UniProt 24275569
S621 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935, 24275569
S638 Phosphorylation phospho.ELM   PhosphoSitePlus 15125835
S664 O-Glycosylation GlyGen 30379171, 29351928
S664 Phosphorylation PhosphoSitePlus
S673 O-Glycosylation GlyGen 30379171, 29351928
K747 Ubiquitination PhosphoSitePlus
T794 Phosphorylation P28482 (MAPK1) phospho.ELM   PhosphoSitePlus   Signor 15125835
E888 Methylation IEDB 32357974
S896 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15125835, 18220336
S936 Phosphorylation PhosphoSitePlus
T1020 Phosphorylation PhosphoSitePlus
S1205 Phosphorylation PhosphoSitePlus
R1211 Methylation PhosphoSitePlus
S1214 Phosphorylation PhosphoSitePlus
T1223 Phosphorylation P28482 (MAPK1) phospho.ELM   PhosphoSitePlus   Signor 15125835
R1230 Methylation PhosphoSitePlus
S1235 Phosphorylation PhosphoSitePlus
S1237 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1242 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S593 Phosphorylation HPRD 17081983, 18452278
S600 Phosphorylation HPRD 17081983
S621 Phosphorylation HPRD 15302935


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S173 P173 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S382 F382 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T389 M389 Biomuta DOID:1319 / brain cancer [ cosmic ]
T389 A389 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y528 C528 Biomuta DOID:1324 / lung cancer [ cosmic ]
K747 E747 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S896 I896 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1020 A1020 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T1020 M1020 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1214 G1214 Biomuta DOID:10534 / stomach cancer [ icgc ]
R1230 W1230 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1242 N1242 Biomuta DOID:363 / uterine cancer [ cosmic ]