iPTMnet Report for O00555 (CACNA1A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00555 / CAC1A_HUMAN
Protein Name Voltage-dependent P/Q-type calcium channel subunit alpha-1A
Gene Name Name: CACNA1A
Synonyms:CACH4,CACN3,CACNL1A4;
Organism Homo sapiens (Human)

PRO ID PR:O00555
DAG View
PRO Name voltage-dependent P/Q-type calcium channel subunit alpha-1A (human)
Definition A voltage-dependent P/Q-type calcium channel subunit alpha-1A that is encoded in the genome of human.
Short Label hCACNA1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00555 (CACNA1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y12 Phosphorylation PhosphoSitePlus
C112 Methylation IEDB 31844290
S211 Phosphorylation PhosphoSitePlus
N283 N-Glycosylation GlyGen 29470411
K378 Ubiquitination PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
S561 Phosphorylation IEDB 35494241
S909 Phosphorylation PhosphoSitePlus
S946 Phosphorylation PhosphoSitePlus
R948 Methylation PhosphoSitePlus
R956 Methylation PhosphoSitePlus
S1121 Phosphorylation PhosphoSitePlus
K1336 Ubiquitination PhosphoSitePlus
K1342 Ubiquitination PhosphoSitePlus
C1368 Methylation IEDB 31844290
Y1420 Phosphorylation PhosphoSitePlus
Y1423 Phosphorylation PhosphoSitePlus
K1425 Ubiquitination PhosphoSitePlus
K1541 Ubiquitination PhosphoSitePlus
K1551 Ubiquitination PhosphoSitePlus
K1585 Acetylation PhosphoSitePlus
S1934 Phosphorylation PhosphoSitePlus
T2114 Phosphorylation PhosphoSitePlus
S2116 Phosphorylation PhosphoSitePlus
T2118 Phosphorylation PhosphoSitePlus
S2119 Phosphorylation PhosphoSitePlus
S2124 Phosphorylation PhosphoSitePlus
S2126 Phosphorylation PhosphoSitePlus
S2262 Phosphorylation PhosphoSitePlus
S2264 Phosphorylation PhosphoSitePlus
S2266 Phosphorylation PhosphoSitePlus
S2268 Phosphorylation PhosphoSitePlus
T2273 Phosphorylation PhosphoSitePlus
T2278 Phosphorylation PhosphoSitePlus
S2300 Phosphorylation PhosphoSitePlus
S2423 Phosphorylation PhosphoSitePlus
S2451 Phosphorylation PhosphoSitePlus
S2464 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y1420 C1420 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S2124 L2124 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2268 R2268 Biomuta DOID:2531 / hematologic cancer [ cosmic ]