iPTMnet Report for O00534 (VWA5A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00534 / VMA5A_HUMAN
Protein Name von Willebrand factor A domain-containing protein 5A
Gene Name Name: VWA5A
Synonyms:BCSC1,LOH11CR2A;
Organism Homo sapiens (Human)

PRO ID PR:O00534
DAG View
PRO Name von Willebrand factor A domain-containing protein 5A (human)
Definition A loss of heterozygosity 11 chromosomal region 2 gene A protein that is encoded in the genome of human.
Short Label hVWA5A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00534 (VWA5A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T9 Phosphorylation PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
T489 Phosphorylation PhosphoSitePlus
K525 Ubiquitination PhosphoSitePlus
K597 Ubiquitination PhosphoSitePlus
S617 Phosphorylation PhosphoSitePlus
K621 Ubiquitination PhosphoSitePlus
K623 Ubiquitination PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
S634 Phosphorylation PhosphoSitePlus
S639 Phosphorylation PhosphoSitePlus
K653 Ubiquitination PhosphoSitePlus
T654 Phosphorylation PhosphoSitePlus
Y660 Phosphorylation PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus
S673 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K72 E72 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K72 T72 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K80 N80 Biomuta DOID:1319 / brain cancer [ icgc ]
K89 E89 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S289 A289 Biomuta DOID:184 / bone cancer [ cosmic ]
K310 N310 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T489 P489 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K621 N621 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S634 P634 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S673 N673 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]