iPTMnet Report for O00533 (CHL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00533 / NCHL1_HUMAN
Protein Name Neural cell adhesion molecule L1-like protein precursor
Gene Name Name: CHL1
Synonyms:CALL;
Organism Homo sapiens (Human)

PRO ID PR:O00533
DAG View
PRO Name neural cell adhesion molecule L1-like protein (human)
Definition A neural cell adhesion molecule L1-like protein that is encoded in the genome of human.
Short Label hCHL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00533 (CHL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N87 N-Glycosylation GlyGen   IEDB 23090970, 29391424, 27550523
N225 N-Glycosylation GlyGen 29391424
N367 N-Glycosylation GlyGen 29391424
N394 N-Glycosylation GlyGen 29671580
N476 N-Glycosylation GlyGen   UniProt 16335952, 29391424
N482 N-Glycosylation GlyGen   UniProt 16335952
N498 N-Glycosylation GlyGen 23090970
N562 N-Glycosylation GlyGen   UniProt 16335952, 29391424, 24190977
S737 Phosphorylation IEDB 35494241
Y747 Phosphorylation PhosphoSitePlus
N767 N-Glycosylation GlyGen   UniProt 16335952, 29391424, 24190977
Y778 Phosphorylation PhosphoSitePlus
N822 N-Glycosylation GlyGen   UniProt 16335952
S871 Phosphorylation PhosphoSitePlus
S876 Phosphorylation PhosphoSitePlus
T933 Phosphorylation PhosphoSitePlus
S935 Phosphorylation PhosphoSitePlus
Y953 Phosphorylation PhosphoSitePlus
T971 Phosphorylation PhosphoSitePlus
N1026 N-Glycosylation GlyGen   UniProt 16335952, 29391424
K1110 Ubiquitination PhosphoSitePlus
S1112 Phosphorylation PhosphoSitePlus
S1127 Phosphorylation PhosphoSitePlus
S1137 Phosphorylation PhosphoSitePlus
S1147 Phosphorylation IEDB   PhosphoSitePlus 35494241
S1150 Phosphorylation PhosphoSitePlus
S1180 Phosphorylation PhosphoSitePlus
S1196 Phosphorylation PhosphoSitePlus
N1197 N-Glycosylation GlyGen 29391424
S1199 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N394 N-Glycosylation PRO 29671580
Site PTM Type PTM Enzyme Score Source PMID
T213 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N482 K482 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y747 C747 Biomuta [ cosmic ]
N767 H767 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y953 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T971 A971 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S1112 A1112 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1112 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S1127 L1127 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1147 N1147 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1180 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1180 L1180 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1180 A1180 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1199 N1199 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1199 R1199 Biomuta DOID:9256 / colorectal cancer [ icgc ]