iPTMnet Report for O00522 (KRIT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00522 / KRIT1_HUMAN
Protein Name Krev interaction trapped protein 1
Gene Name Name: KRIT1
Synonyms:CCM1;
Organism Homo sapiens (Human)

PRO ID PR:O00522
DAG View
PRO Name Krev interaction trapped protein 1 (human)
Definition A Krev interaction trapped protein 1 that is encoded in the genome of human.
Short Label hKRIT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00522 (KRIT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus   RLIMS-P 33443102
S32 Phosphorylation PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
T151 Phosphorylation PhosphoSitePlus
K224 Acetylation PhosphoSitePlus
Y230 Phosphorylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
Y252 Phosphorylation PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
Y431 Phosphorylation PhosphoSitePlus
Y605 Phosphorylation PhosphoSitePlus
K606 Ubiquitination PhosphoSitePlus
Y659 Phosphorylation PhosphoSitePlus
T732 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y605 Phosphorylation HPRD 20058876
Site PTM Type PTM Enzyme Score Source PMID
Y557 Phosphorylation HPRD 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S22 I22 Biomuta DOID:11934 / head and neck cancer [ icgc ]
Y557 C557 Biomuta DOID:9256 / colorectal cancer [ cosmic ]