iPTMnet Report for O00506 (STK25)
Protein Information
| UniProt AC / UniProt ID | O00506 / STK25_HUMAN |
| Protein Name | Serine/threonine-protein kinase 25 |
| Gene Name | Name: STK25 Synonyms:SOK1,YSK1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O00506 |
| PRO Name | serine/threonine-protein kinase 25 (human) |
| Definition | A serine/threonine-protein kinase 25 that is encoded in the genome of human. |
| Short Label | hSTK25 |
| Category | organism-gene |
DAG ViewO00506 (STK25) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S12 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K22 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S30 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y35 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K36 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K43 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K142 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T166 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T168 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332, 17287340 | ||
| K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T174 | Phosphorylation | O00506 (STK25) | score3 | PhosphoSitePlus RLIMS-P UniProt | 15037601 | |
| T178 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S231 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K253 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K262 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K276 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K335 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S342 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17287340 | ||
| T360 | Phosphorylation | score1 | PhosphoSitePlus |
O00506 (STK25) as PTM Enzyme
|
Substrate | Site | Score | Source | PMID |
|---|---|---|---|---|---|
| O00506 (STK25) | T174 | score4 | HPRD UniProt | 18452278, 15037601 | |
| P63104 (YWHAZ) | S58 | score3 | HPRD neXtProt | 15037601 | |
| Q9BSQ5 (CCM2) | S384 | score3 | neXtProt PhosphoSitePlus Signor | 22782892 | |
| Q9BUL8 (PDCD10) | S39 | score3 | neXtProt PhosphoSitePlus Signor | 19370760 | |
| Q9BUL8 (PDCD10) | T43 | score3 | neXtProt PhosphoSitePlus Signor | 19370760 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S30 | L30 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| Y35 | C35 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| K36 | T36 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T168 | M168 | Biomuta | DOID:1725 / peritoneum cancer [ cosmic ] | |
| S342 | L342 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
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