Protein Information

Cytoscape View


UniProt AC / UniProt ID O00487 / PSDE_HUMAN
Protein Name 26S proteasome non-ATPase regulatory subunit 14
Gene Name Name: PSMD14
Synonyms:POH1;
Organism Homo sapiens (Human)

PRO ID PR:O00487
DAG View
PRO Name 26S proteasome non-ATPase regulatory subunit 14 (human)
Definition A 26S proteasome non-ATPase regulatory subunit 14 that is encoded in the genome of human.
Short Label hPSMD14
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00487 (PSMD14) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y32 Phosphorylation HPRD   PhosphoSitePlus 15592455
S34 Phosphorylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
S150 Phosphorylation HPRD   PhosphoSitePlus   UniProt 24275569, 17693683
K152 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
T177 Phosphorylation HPRD 20068231
S179 Phosphorylation HPRD 20068231
K186 Ubiquitination PhosphoSitePlus
S188 O-Glycosylation GlyGen 23301498, 28510447, 29351928
K209 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus   UniProt 17323924
Y234 Phosphorylation PhosphoSitePlus
C238 S-Nitrosylation dbSNO 26338901
K239 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
T266 Phosphorylation PhosphoSitePlus   UniProt 23186163
K273 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y32 C32 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K154 R154 Biomuta DOID:3571 / liver cancer [ tcga ]
S179 L179 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
C238 R238 Biomuta DOID:1909 / melanoma [ cosmic ]
K253 N253 Biomuta DOID:363 / uterine cancer [ tcga ]
K273 N273 Biomuta DOID:3571 / liver cancer [ icgc ]