iPTMnet Report for O00483 (NDUFA4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00483 / NDUA4_HUMAN
Protein Name Cytochrome c oxidase subunit NDUFA4
Gene Name Name: NDUFA4
Organism Homo sapiens (Human)

PRO ID PR:O00483
DAG View
PRO Name cytochrome c oxidase subunit NDUFA4 (human)
Definition A cytochrome c oxidase subunit NDUFA4 that is encoded in the genome of human.
Short Label hNDUFA4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00483 (NDUFA4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K10 Methylation PhosphoSitePlus
C44 Methylation IEDB 31844290
R47 Methylation PhosphoSitePlus
K55 Acetylation PhosphoSitePlus
K55 Methylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
Y62 Phosphorylation PhosphoSitePlus
K63 Acetylation PhosphoSitePlus
K63 Methylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
Y65 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 33640490, 23186163
Y71 Phosphorylation PhosphoSitePlus
K73 Acetylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K10 N10 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K55 I55 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y71 H71 Biomuta DOID:2174 / ocular cancer [ cosmic ]