iPTMnet Report for O00478 (BTN3A3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00478 / BT3A3_HUMAN
Protein Name Butyrophilin subfamily 3 member A3 precursor
Gene Name Name: BTN3A3
Synonyms:BTF3;
Organism Homo sapiens (Human)

PRO ID PR:O00478
DAG View
PRO Name butyrophilin subfamily 3 member A3 (human)
Definition A butyrophilin subfamily 3 member A3 that is encoded in the genome of human.
Short Label hBTN3A3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00478 (BTN3A3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C52 Methylation IEDB 31844290
K83 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
R112 Methylation PhosphoSitePlus
N115 N-Glycosylation GlyGen   UniProt 24190977, 19349973
K123 Ubiquitination PhosphoSitePlus
C126 Methylation IEDB 31844290
K231 Ubiquitination PhosphoSitePlus
Y295 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
Y319 Phosphorylation PhosphoSitePlus
T537 Phosphorylation PhosphoSitePlus
Y584 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R112 Q112 Biomuta DOID:4362 / cervical cancer [ icgc ]
R112 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
Y295 N295 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S303 N303 Biomuta DOID:3571 / liver cancer [ cosmic ]