iPTMnet Report for O00471 (EXOC5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00471 / EXOC5_HUMAN
Protein Name Exocyst complex component 5
Gene Name Name: EXOC5
Synonyms:SEC10,SEC10L1;
Organism Homo sapiens (Human)

PRO ID PR:O00471
DAG View
PRO Name exocyst complex component 5 (human)
Definition An exocyst complex component 5 that is encoded in the genome of human.
Short Label hEXOC5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00471 (EXOC5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
T3 Phosphorylation HPRD   PhosphoSitePlus 18491316
T4 Phosphorylation HPRD 18491316
K87 Ubiquitination PhosphoSitePlus
T122 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 23186163
K132 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
R177 Methylation PhosphoSitePlus
C194 Methylation IEDB 31844290
S210 Phosphorylation PhosphoSitePlus
Y225 Phosphorylation PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K297 Acetylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
T328 Phosphorylation PhosphoSitePlus
T332 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
K557 Ubiquitination PhosphoSitePlus
C661 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K87 R87 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K557 Q557 Biomuta DOID:263 / kidney cancer [ cosmic ]