Protein Information

Cytoscape View


UniProt AC / UniProt ID O00462 / MANBA_HUMAN
Protein Name Beta-mannosidase precursor
Gene Name Name: MANBA
Synonyms:MANB1;
Organism Homo sapiens (Human)

PRO ID PR:O00462
DAG View
PRO Name beta-mannosidase (human)
Definition A beta-mannosidase that is encoded in the genome of human.
Short Label hMANBA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00462 (MANBA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N77 N-Glycosylation GlyGen 23090970, 29741879, 24190977
K85 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
Y161 Phosphorylation PhosphoSitePlus
N280 N-Glycosylation GlyGen 23090970, 24190977
T325 Phosphorylation PhosphoSitePlus
Y485 Phosphorylation IEDB 35494241
Y597 Phosphorylation PhosphoSitePlus
C800 Methylation IEDB 31844290
T847 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N77 Y77 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y161 H161 Biomuta DOID:2531 / hematologic cancer [ cosmic ]