Protein Information

Cytoscape View

UniProt AC / UniProt ID O00462 / MANBA_HUMAN
Protein Name Beta-mannosidase precursor
Gene Name Name: MANBA
Organism Homo sapiens (Human)

PRO ID PR:O00462
DAG View
PRO Name beta-mannosidase (human)
Definition A beta-mannosidase that is encoded in the genome of human.
Short Label hMANBA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O00462 (MANBA) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K85 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
Y161 Phosphorylation PhosphoSitePlus
T325 Phosphorylation PhosphoSitePlus
Y597 Phosphorylation PhosphoSitePlus
T847 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y161 H161 Biomuta DOID:2531 / hematologic cancer [ icgc ]
T325 A325 Biomuta DOID:363 / uterine cancer [ tcga ]