iPTMnet Report for O00458 (IFRD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00458 / IFRD1_HUMAN
Protein Name Interferon-related developmental regulator 1
Gene Name Name: IFRD1
Organism Homo sapiens (Human)

PRO ID PR:O00458
DAG View
PRO Name interferon-related developmental regulator 1 (human)
Definition An interferon-related developmental regulator 1 that is encoded in the genome of human.
Short Label hIFRD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00458 (IFRD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T9 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
S21 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
K94 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
Y116 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
K431 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y116 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K94 N94 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K325 N325 Biomuta DOID:1324 / lung cancer [ cosmic ]
K357 T357 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]