iPTMnet Report for O00451 (GFRA2)
Protein Information
| UniProt AC / UniProt ID | O00451 / GFRA2_HUMAN |
| Protein Name | GDNF family receptor alpha-2 precursor |
| Gene Name | Name: GFRA2 Synonyms:GDNFRB,RETL2,TRNR2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O00451 |
| PRO Name | GDNF family receptor alpha-2 (human) |
| Definition | A GDNF family receptor alpha-2 that is encoded in the genome of human. |
| Short Label | hGFRA2 |
| Category | organism-gene |
DAG ViewO00451 (GFRA2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N52 | N-Glycosylation | score1 | GlyGen | 23090970, 24190977 | ||
| S179 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T396 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T401 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S441 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S444 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T396 | I396 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
| S441 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S444 | R444 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] |
