iPTMnet Report for O00445 (SYT5)
Protein Information
| UniProt AC / UniProt ID | O00445 / SYT5_HUMAN |
| Protein Name | Synaptotagmin-5 |
| Gene Name | Name: SYT5 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O00445 |
| PRO Name | synaptotagmin-5 (human) |
| Definition | A synaptotagmin-5 that is encoded in the genome of human. |
| Short Label | hSYT5 |
| Category | organism-gene |
O00445 (SYT5) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T15 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y81 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y196 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S202 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K268 | Acetylation | score1 | PhosphoSitePlus | |||
| Y278 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T15 | R15 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T59 | R59 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y196 | H196 | Biomuta | [ cosmic ] | |
| K268 | T268 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| Y278 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
DAG View