iPTMnet Report for O00423 (EML1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00423 / EMAL1_HUMAN
Protein Name Echinoderm microtubule-associated protein-like 1
Gene Name Name: EML1
Synonyms:EMAP1,EMAPL,EMAPL1;
Organism Homo sapiens (Human)

PRO ID PR:O00423
DAG View
PRO Name echinoderm microtubule-associated protein-like 1 (human)
Definition An echinoderm microtubule-associated protein-like 1 that is encoded in the genome of human.
Short Label hEML1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00423 (EML1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T90 Phosphorylation PhosphoSitePlus
T108 Phosphorylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus   UniProt 24275569
T133 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
T161 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
Y186 Phosphorylation PhosphoSitePlus
K202 Acetylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
T315 Phosphorylation PhosphoSitePlus
Y396 Phosphorylation PhosphoSitePlus
T448 Phosphorylation PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
T473 Phosphorylation PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
Y491 Phosphorylation PhosphoSitePlus
S755 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S134 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S110 F110 Biomuta DOID:4159 / skin cancer [ cosmic ]
S113 F113 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
T158 R158 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S160 F160 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y396 * Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
S476 L476 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3565 / meningioma [ cosmic ]