iPTMnet Report for O00409 (FOXN3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00409 / FOXN3_HUMAN
Protein Name Forkhead box protein N3
Gene Name Name: FOXN3
Synonyms:C14orf116,CHES1;
Organism Homo sapiens (Human)

PRO ID PR:O00409
DAG View
PRO Name forkhead box protein N3 (human)
Definition A forkhead box protein N3 that is encoded in the genome of human.
Short Label hFOXN3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00409 (FOXN3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus   UniProt 19690332
S97 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
T297 Phosphorylation PhosphoSitePlus
T316 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S85 N85 Biomuta DOID:363 / uterine cancer [ icgc ]
S97 Y97 Biomuta DOID:1324 / lung cancer [ cosmic ]
S97 F97 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S167 L167 Biomuta DOID:1324 / lung cancer [ cosmic ]
S324 Y324 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S349 L349 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S432 R432 Biomuta DOID:3571 / liver cancer [ cosmic ]