iPTMnet Report for O00339 (MATN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00339 / MATN2_HUMAN
Protein Name Matrilin-2 precursor
Gene Name Name: MATN2
ORFNames:UNQ193/PRO219;
Organism Homo sapiens (Human)

PRO ID PR:O00339
DAG View
PRO Name matrilin-2 (human)
Definition A matrilin-2 that is encoded in the genome of human.
Short Label hMATN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00339 (MATN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T40 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
Y101 Phosphorylation PhosphoSitePlus
K115 Acetylation PhosphoSitePlus
K125 Acetylation PhosphoSitePlus
T134 Phosphorylation PhosphoSitePlus
T136 Phosphorylation PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
Y432 Phosphorylation PhosphoSitePlus
T705 Phosphorylation PhosphoSitePlus
K730 Acetylation PhosphoSitePlus
T860 O-Glycosylation GlyGen 30459171
T866 O-Glycosylation GlyGen 30459171
S894 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
T895 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S901 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T902 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S905 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
Site PTM Type PTM Enzyme Score Source PMID
S894 Phosphorylation HPRD 17525332
T895 Phosphorylation HPRD 17525332
Site PTM Type PTM Enzyme Score Source PMID
S875 Phosphorylation HPRD 17525332
T876 Phosphorylation HPRD 17525332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K125 N125 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T169 I169 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]