iPTMnet Report for O00327 (BMAL1)
Protein Information
UniProt AC / UniProt ID | O00327 / BMAL1_HUMAN |
Protein Name | Basic helix-loop-helix ARNT-like protein 1 |
Gene Name | Name: BMAL1 Synonyms:ARNTL,BHLHE5,MOP3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O00327 |
PRO Name | basic helix-loop-helix ARNT-like protein 1 (human) |
Definition | A basic helix-loop-helix ARNT-like protein 1 that is encoded in the genome of human. |
Short Label | hBMAL1 |
Category | organism-gene |
O00327 (BMAL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Phosphorylation | score1 | PRO | ||||
S17 | Phosphorylation | P49841 (GSK3B) | score3 | PhosphoSitePlus RLIMS-P Signor | 20049328 | |
T21 | Phosphorylation | P49841 (GSK3B) | score3 | PhosphoSitePlus RLIMS-P Signor | 20049328 | |
S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
T44 | Phosphorylation | score1 | PhosphoSitePlus | |||
S49 | Phosphorylation | score1 | PhosphoSitePlus | |||
T52 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y63 | Phosphorylation | score1 | PhosphoSitePlus | |||
S78 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 23229515, 27153104 | ||
S90 | Phosphorylation | score1 | RLIMS-P | 19330005, 26562092, 24312621 | ||
K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
K205 | Ubiquitination | score1 | PhosphoSitePlus | |||
T224 | Phosphorylation | score1 | PhosphoSitePlus | |||
K259 | Sumoylation | score1 | PhosphoSitePlus | |||
S284 | Phosphorylation | score1 | PhosphoSitePlus | |||
T294 | Phosphorylation | score1 | PhosphoSitePlus | |||
K398 | Ubiquitination | score1 | PhosphoSitePlus | |||
T400 | Phosphorylation | score1 | PhosphoSitePlus | |||
T401 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y404 | Phosphorylation | score1 | PhosphoSitePlus | |||
K409 | Ubiquitination | score1 | PhosphoSitePlus | |||
S418 | O-Glycosylation | score2 | GlyGen | 23395176 | ||
T477 | Phosphorylation | score1 | PhosphoSitePlus | |||
T480 | Phosphorylation | score1 | PhosphoSitePlus | |||
T488 | Phosphorylation | score1 | PhosphoSitePlus | |||
S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
T527 | Phosphorylation | score1 | PhosphoSitePlus | |||
K538 | Acetylation | score1 | PhosphoSitePlus | |||
S592 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K223 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S78 | Phosphorylation | score0 | HPRD | 18077418 | ||
K271 | Acetylation | score1 | PhosphoSitePlus | |||
K272 | Acetylation | score1 | PhosphoSitePlus | |||
K276 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K271 | N271 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |