iPTMnet Report for O00327 (BMAL1)
Protein Information
| UniProt AC / UniProt ID | O00327 / BMAL1_HUMAN |
| Protein Name | Basic helix-loop-helix ARNT-like protein 1 |
| Gene Name | Name: BMAL1 Synonyms:ARNTL,BHLHE5,MOP3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O00327 |
| PRO Name | basic helix-loop-helix ARNT-like protein 1 (human) |
| Definition | A basic helix-loop-helix ARNT-like protein 1 that is encoded in the genome of human. |
| Short Label | hBMAL1 |
| Category | organism-gene |
O00327 (BMAL1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Phosphorylation | score1 | PRO | ||||
| S17 | Phosphorylation | P49841 (GSK3B) | score3 | PhosphoSitePlus RLIMS-P Signor | 20049328 | |
| T21 | Phosphorylation | P49841 (GSK3B) | score3 | PhosphoSitePlus RLIMS-P Signor | 20049328 | |
| S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T44 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S49 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T52 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y63 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S78 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 23229515, 27153104 | ||
| S90 | Phosphorylation | score1 | RLIMS-P | 19330005, 26562092, 24312621 | ||
| K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K205 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T224 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K259 | Sumoylation | score1 | PhosphoSitePlus | |||
| S284 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K398 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T400 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T401 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y404 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K409 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S418 | O-Glycosylation | score2 | GlyGen | 23395176 | ||
| T477 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T480 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T488 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T527 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K538 | Acetylation | score1 | PhosphoSitePlus | |||
| S592 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K223 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S78 | Phosphorylation | score0 | HPRD | 18077418 | ||
| K271 | Acetylation | score1 | PhosphoSitePlus | |||
| K272 | Acetylation | score1 | PhosphoSitePlus | |||
| K276 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K271 | N271 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View