Protein Information

Cytoscape View


UniProt AC / UniProt ID O00268 / TAF4_HUMAN
Protein Name Transcription initiation factor TFIID subunit 4
Gene Name Name: TAF4
Synonyms:TAF2C,TAF2C1,TAF4A,TAFII130,TAFII135;
Organism Homo sapiens (Human)

PRO ID PR:O00268
DAG View
PRO Name transcription initiation factor TFIID subunit 4 (human)
Definition A transcription initiation factor TFIID subunit 4 that is encoded in the genome of human.
Short Label hTAF4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00268 (TAF4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
T47 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus   UniProt 23186163
T396 Phosphorylation PhosphoSitePlus
T409 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
R414 Methylation PhosphoSitePlus
T415 Phosphorylation PhosphoSitePlus
S421 Phosphorylation PhosphoSitePlus
R424 Methylation PhosphoSitePlus   UniProt 24129315
R435 Methylation PhosphoSitePlus   UniProt 24129315
R491 Methylation PhosphoSitePlus
R516 Methylation PhosphoSitePlus
S528 O-Glycosylation PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
T571 Phosphorylation PhosphoSitePlus
K611 Ubiquitination PhosphoSitePlus
K621 Ubiquitination PhosphoSitePlus
K631 Ubiquitination PhosphoSitePlus
S648 Phosphorylation PhosphoSitePlus
Y652 Phosphorylation PhosphoSitePlus
S660 Phosphorylation PhosphoSitePlus
R754 Methylation PhosphoSitePlus
R769 Methylation PhosphoSitePlus
R774 Methylation PhosphoSitePlus
K795 Acetylation PhosphoSitePlus
S827 Phosphorylation PhosphoSitePlus
S857 Phosphorylation HPRD   PhosphoSitePlus 20068231
T862 Phosphorylation HPRD 20068231
K945 Ubiquitination PhosphoSitePlus
S1027 Phosphorylation PhosphoSitePlus
S1032 Phosphorylation PhosphoSitePlus
S1036 Phosphorylation PhosphoSitePlus
S1042 Phosphorylation PhosphoSitePlus
T1046 Phosphorylation PhosphoSitePlus
T1056 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T396 I396 Biomuta DOID:3571 / liver cancer [ icgc ]
R491 H491 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
R491 C491 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S528 Y528 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
S543 * Biomuta DOID:3571 / liver cancer [ icgc ]
S543 L543 Biomuta DOID:11934 / head and neck cancer [ tcga ]
T571 A571 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K631 N631 Biomuta DOID:363 / uterine cancer [ tcga ]
R754 L754 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
R754 Q754 Biomuta DOID:363 / uterine cancer [ tcga ]
K795 R795 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S827 L827 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S857 F857 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
S857 C857 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
S1036 L1036 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1909 / melanoma [ icgc, tcga ]
T1046 P1046 Biomuta DOID:10534 / stomach cancer [ icgc, tcga ]
T1056 M1056 Biomuta DOID:9256 / colorectal cancer [ icgc ]