Protein Information

Cytoscape View


UniProt AC / UniProt ID O00241 / SIRB1_HUMAN
Protein Name Signal-regulatory protein beta-1 precursor
Gene Name Name: SIRPB1
Organism Homo sapiens (Human)

PRO ID PR:O00241
DAG View
PRO Name signal-regulatory protein beta-1 isoforms 1/2 (human)
Definition A signal-regulatory protein beta-1 (human), isoforms 1 and 2.
Short Label hSIRPB1/iso:[1/2]
Category organism-seqgroup

Interactive Sequence View

Select/align proteoforms across species


O00241 (SIRPB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K82 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
Y119 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
N244 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 24190977, ...29741879
N266 N-Glycosylation GlyGen 24190977
N269 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N289 N-Glycosylation GlyGen 24190977
N291 N-Glycosylation GlyGen 24190977


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K82 E82 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
K97 R97 Biomuta DOID:2394 / ovarian cancer [ icgc ] DOID:2994 / germ cell cancer [ cosmic ]
N269 D269 Biomuta DOID:3571 / liver cancer [ tcga ]