iPTMnet Report for O00241 (SIRPB1)
Protein Information
| UniProt AC / UniProt ID | O00241 / SIRB1_HUMAN |
| Protein Name | Signal-regulatory protein beta-1 precursor |
| Gene Name | Name: SIRPB1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O00241 |
| PRO Name | signal-regulatory protein beta-1 isoforms 1/2 (human) |
| Definition | A signal-regulatory protein beta-1 (human), isoforms 1 and 2. |
| Short Label | hSIRPB1/iso:[1/2] |
| Category | organism-seqgroup |
DAG ViewO00241 (SIRPB1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y119 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N244 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 23090970, 24190977, ... | ||
| N266 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N269 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| N289 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N291 | N-Glycosylation | score1 | GlyGen | 24190977 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K82 | E82 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| K97 | R97 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| N269 | D269 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] |
