iPTMnet Report for O00238 (BMPR1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00238 / BMR1B_HUMAN
Protein Name Bone morphogenetic protein receptor type-1B precursor
Gene Name Name: BMPR1B
Organism Homo sapiens (Human)

PRO ID PR:O00238
DAG View
PRO Name bone morphogenetic protein receptor type-1B (human)
Definition A BMP receptor type-1B that is encoded in the genome of human.
Short Label hBMPR1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00238 (BMPR1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
S92 Phosphorylation PhosphoSitePlus
T97 Phosphorylation PhosphoSitePlus
T109 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S175 Phosphorylation PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
K493 Ubiquitination PhosphoSitePlus


O00238 (BMPR1B) as PTM Enzyme



Substrate Site Score Source PMID
O95630-1 (STAMBP) S2 HPRD 11483516
O95630-1 (STAMBP) S48 HPRD 11483516
O95630-1 (STAMBP) S243 HPRD 11483516
O95630-1 (STAMBP) S245 HPRD 11483516
O95630-1 (STAMBP) S247 HPRD 11483516
Q15796 (SMAD2) S464 phospho.ELM   PhosphoSitePlus 9136927
Q15796 (SMAD2) S465 phospho.ELM   PhosphoSitePlus 9136927
Q15796 (SMAD2) S467 phospho.ELM   PhosphoSitePlus 9136927
Q15797 (SMAD1) S462 phospho.ELM   PhosphoSitePlus   Signor 9335504, 9136927
Q15797 (SMAD1) S463 phospho.ELM   PhosphoSitePlus   Signor 9335504, 9136927
Q15797 (SMAD1) S465 phospho.ELM   PhosphoSitePlus   Signor 9335504, 9136927


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046496 (hBMPR1B/SigPep-/PhosSer+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y290 H290 Biomuta DOID:4159 / skin cancer [ cosmic ]
S402 G402 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]