iPTMnet Report for O00231 (PSMD11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00231 / PSD11_HUMAN
Protein Name 26S proteasome non-ATPase regulatory subunit 11
Gene Name Name: PSMD11
Organism Homo sapiens (Human)

PRO ID PR:O00231
DAG View
PRO Name 26S proteasome non-ATPase regulatory subunit 11 (human)
Definition A 26S proteasome non-ATPase regulatory subunit 11 that is encoded in the genome of human.
Short Label hPSMD11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00231 (PSMD11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
R11 Methylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus   UniProt 23186163, 17323924, 18669648, ...26669444, 24275569
S14 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 26669444
R20 Methylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus   UniProt 23186163
S29 Phosphorylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
T60 Phosphorylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
Y72 Phosphorylation PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
K141 Acetylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
Y201 Phosphorylation PhosphoSitePlus
C202 Methylation IEDB 31844290
C202 S-Nitrosylation dbSNO 19483679, 2212679, 22126794
K205 Ubiquitination PhosphoSitePlus
T209 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
C257 Methylation IEDB 31844290
T263 Phosphorylation IEDB 35494241
S272 Phosphorylation PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
T284 Phosphorylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
C289 Methylation IEDB 31844290
C289 S-Nitrosylation dbSNO 19483679
K295 Ubiquitination PhosphoSitePlus
S298 Phosphorylation PhosphoSitePlus
K304 Methylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
T396 Phosphorylation PhosphoSitePlus
Y397 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
Y415 Phosphorylation PhosphoSitePlus
K417 Acetylation PhosphoSitePlus
K417 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation HPRD 18669648
S79 Phosphorylation HPRD 20068231
S81 Phosphorylation HPRD 20068231
S272 Phosphorylation HPRD 17081983, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S14 F14 Biomuta DOID:1319 / brain cancer [ cosmic ]
R20 P20 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R20 L20 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S29 Y29 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S29 P29 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K59 N59 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K71 N71 Biomuta DOID:363 / uterine cancer [ icgc ]
Y72 F72 Biomuta DOID:1324 / lung cancer [ cosmic ]
C202 W202 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
C202 Y202 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S214 L214 Biomuta DOID:1324 / lung cancer [ cosmic ]
S214 P214 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K288 Q288 Biomuta DOID:363 / uterine cancer [ icgc ]
K325 Q325 Biomuta DOID:1324 / lung cancer [ cosmic ]
K358 E358 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K372 N372 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]