iPTMnet Report for O00222 (GRM8)
Protein Information
| UniProt AC / UniProt ID | O00222 / GRM8_HUMAN |
| Protein Name | Metabotropic glutamate receptor 8 precursor |
| Gene Name | Name: GRM8 Synonyms:GPRC1H,MGLUR8; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O00222 |
| PRO Name | metabotropic glutamate receptor 8 (human) |
| Definition | A metabotropic glutamate receptor 8 that is encoded in the genome of human. |
| Short Label | hGRM8 |
| Category | organism-gene |
O00222 (GRM8) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S107 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y471 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S855 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T864 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S867 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K872 | Acetylation | score1 | PhosphoSitePlus | |||
| K882 | Sumoylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S867 | I867 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S867 | N867 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K872 | N872 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View